Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11113-2
BACH2 restrains activation of the fetal-haemoglobin-encoding γ-globin genes, while loss of BACH2 enhances NRF2 chromatin occupancy and promotes the formation of activation foci at the γ-globin genes.General
Human genetics implicates a BACH2–NRF2 axis in fetal haemoglobin activation
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Source：https://www.nature.com/articles/s41586-026-11113-2
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