arXiv:2610.13119v1 Announce Type: new Abstract: Collecting dexterous manipulation demonstrations for each robot hand requires repeated task-specific data acquisition. We ask whether one shared corpus of natural human demonstrations can instead serve as a reusable data interface for different dexterous hands, without collecting task demonstrations on each target robot. We present Human2Dex, a wrist-centric human demonstration interface that separates shared human observation and motion semantics from embodiment-specific execution. It aligns observations through local hand-appearance adaptation and a shared 21-point hand representation with consistent structural semantics across human and robot observations. It constructs executable supervision by retargeting fused human hand motion to each target hand, and introduces the Grasp-Pocket Interaction Representation (GPIR) to express tracked objects relative to a hand-centered Functional Grasp Pocket. The corpus is converted into separate training sets for Linker O6 and Wuji, while action labels, normalization, training, and diffusion-policy checkpoints remain hand-specific. Across six real-world tasks, Human2Dex achieves 109/120 (90.8%) successes on Linker O6 and 97/120 (80.8%) on Wuji. Across both hands, Human-Raw achieves 63/240 (26.3%) successes, whereas the complete Human2Dex configuration achieves 206/240 (85.8%). These results support the use of wrist-centric human demonstrations as a reusable interface across calibrated dexterous hands while retaining embodiment-specific policy learning. The project website is publicly available at https://human2dex.pages.dev/.