arXiv:2610.34789v1 Announce Type: new Abstract: Quadrotor interceptors equipped with strapdown cameras offer a low-cost solution for physically countering unauthorized UAVs. However, this configuration inherently couples vehicle maneuvering and camera pointing, creating a conflict between rapid closing and maintaining target visibility. We present interception-oriented spherical-bearing nonlinear model predictive control (ISB-NMPC), which couples spherical-bearing prediction with nonlinear quadrotor dynamics to jointly optimize target-directed closing motion and visibility. An attitude-compensated extended Kalman filter on S^2 estimates target bearing motion, compensates for perception delay, and predicts target bearings to guide scale-adaptive detection. Across 30 paired simulation trials, ISB-NMPC achieves an interception success rate of 86.7%, the highest among the evaluated controllers, with a mean per-trial target-visible time of 99.11%. Outdoor flights demonstrate acquisition of a 30 cm target at approximately 150 m, with interceptor speed reaching 17 m/s in the long-range flight and approximately 14 m/s while pursuing a quadrotor-towed maneuvering target. The software and hardware are open source at https://github.com/HOLYNOTBAD/ISB-NMPC and https://github.com/HOLYNOTBAD/holydrone, respectively.