arXiv:2610.07515v1 Announce Type: new Abstract: Accurately modeling and tracking the deformation of soft tissue is critical for a wide range of interventional and surgical procedures. However, current methods struggle in scenarios involving topological changes, such as cutting and dissection, due to the inherent non-linearity and discontinuity introduced by explicit changes in connectivity. In this work, we present a novel, fully differentiable framework that enables robust estimation and modeling of topological changes during deformable tracking. Our method introduces a continuous, sigmoid-based formulation to smooth the otherwise discrete event of tissue cutting, making it amenable to gradient-based optimization within a differentiable Position-Based Dynamics (PBD) simulation. To account for uncertainty and improve robustness in the presence of noisy visual data, we incorporate Stein Variational Gradient Descent (SVGD) for particle-based probabilistic inference, generating multiple hypotheses for topological state estimation. Building on this foundation, we develop an autonomous dissection algorithm for thin-shell tissues that leverages topological updates to guide closed-loop cutting trajectory control. We evaluate our approach in both simulated and real-world electrosurgical environments, demonstrating significant improvements in topological estimation accuracy and dissection precision over existing methods. Our results highlight the potential of this framework to advance automation in soft-tissue surgical procedures by enabling reliable perception and control in the presence of complex structural changes.