arXiv:2610.26916v1 Announce Type: cross Abstract: Space-based artificial intelligence (AI) is moving beyond isolated onboard processing toward constellation-scale computing over optical inter-satellite links (OISLs). Yet current infrastructures remain fragmented, making end-to-end (E2E) coordination across heterogeneous and multi-vendor systems difficult. This article examines the StarMind vision and develops a reference framework for distributed orbital computing. It organizes the system into five layers and defines six standardizable interfaces that link mission intent to resource conditions and trustworthy result delivery. The framework also clarifies the operational constraints that determine whether orbital cooperation is worthwhile. In a representative synthetic aperture radar/interferometric SAR (SAR/InSAR) case study, the framework reduces E2E latency to 41-min, compared with 61-min for localized onboard computing and 146-min for ground-based processing. This gain does not rely on faster processors in orbit. Instead, it comes from reducing contact waiting and urgent Earth downlink traffic through resource-aware task placement and gateway selection. Feasibility analysis shows that the proposed framework is more effective when source datasets are large, output products are compact, and optical inter-satellite link capacity is sufficient. When these conditions are absent, conventional processing may remain preferable. Finally, we discuss research opportunities in joint task partitioning and cross-domain orchestration, hierarchical federated intelligence, and large model-enabled intelligence to advance an interoperable space-ground computing continuum.