Nature, Published online: 11 November 2026; doi:10.1038/s41586-026-11276-y
PRIMPOL is recruited to stalled forks through an interaction with the replicative helicase CDC45–MCM2–7–GINS, facilitating primer handover from PRIMPOL to the high-fidelity polymerase ε, minimizing mutagenic DNA synthesis.Backend
The molecular basis of replication fork restart via repriming by PRIMPOL
Nature News0 views
Source：https://www.nature.com/articles/s41586-026-11276-y
PreviousGive biologists the space to be curious, not just better toolsNextDomain-alteration chimeras rewire oncogenic complexes in prostate cancer
Related posts
AWS had its agents build a free and open emulator for AWS. They now maintain it, too.
0The New Stack
Nmrs 3.5.12 release - a typed, async Rust library for NetworkManager
0Rust Users Forum
Gemini Decisions API: Fast, calibrated multimodal decisions
0Google AI Blog
Test your applications against AWS locally with AWS Emulator
0AWS Blog
Vercel Connect Stripe Restricted Keys for AI Agents
0dev.to
Hosting a 24/7 livestream with a terminal
0dev.to